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The Effects of L-Arginine (the Precursor of Nitric Oxide) and L-NAME (Nitric Oxide Synthase Inhibitor) on Coronary Angiogenesis in Normal Rats
مجله دانشکده پزشکی اصفهان
Nitric oxide (NO) has beneficial effects on cardiovascular system including improvement of angiogenesis. The aim of this study was to evaluate the effects of L-arginine (the precursor of NO) and L-NG-nitroarginine methyl ester (L-NAME) (NO synthase inhibitor) on serum vascular endothelial growth factor (VEGF) and coronary angiogenesis in normal rats. Methods: In this study, 18 male rats were randomly divided into 3 groups. Groups 1 and 2 received intraperitoneal L-NAME (10 mg/kg/day) anddoaj:b2634e1e2fb440eca290fbf91f41da6c fatcat:uqgmi3lwljdyvdgclukj6uljka