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The effects of T-activin, the thymus-derived polypeptide, on the content level of monoamines and their metabolites in frontal cerebral cortex, striatum, hypothalamus, nucleus accumbens and hippocampus of rats under emotional stress conditions using HPLC technique have been studied. The substance was shown to reduce the indices of emotional tension and to improve adaptation in stressful conditions at rats that may be the evidence of the anxiolytic action of T-activin. It may be suggested thatdoaj:64e3a96ccd424e0fb9f1cd06c24c2d9c fatcat:kgzzeyg7cbef5edlfcf67vh4pq