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We investigate the variability of one of the most often used complexity measures in the analysis of the time series of RR intervals, i.e. Sample Entropy. The analysis is carried out for a dense matrix of possible r thresholds in 79 24h recordings, for segments consisting of 5000 consecutive beats, randomly selected from the whole recording. It is repeated for the same recordings in random order. This study is made possible by the novel NCM algorithm which is many orders of magnitude faster thandoi:10.17512/jamcm.2018.2.09 fatcat:73fa7lncxrafxo5f2vpxnwclc4