INHIBITION OF STAPHYLOCOCCAL ENTEROTOXIN B FORMATION BY CELL WALL BLOCKING AGENTS AND OTHER COMPOUNDS [report]

Mischa E. Friedman
1968 unpublished
The ezcellent technical assistance of Guy M. Dayhoff is "qcknowledged. ABSTRACT Enterotoxin B formation by Staohvlococcus aureus 56 was inhibited by Tveen 80, oleic acid, sodium deoxycholate, penicillin, D-cycloserine, or bacitracin. Toxin formation by strain 243 was sensitive to oleic acid, sodium deoxycholate, sodium lauryl sulfate, D-cycloserine, or bacitracin. The effect of D-cycloserine was reversed by D-alanine with strain 243 but not with strain S6. Neither penicillin nor bacitracin
more » ... ited a-hemolysin or coagulass activity of strain S6; however, 0.118 4moles of D-cycloserine per ml of liquid medium increased the cz-hemolysin titer more than eightfold. Pigmentation of straetc 243 was reduced by oleic acid, sodium deozycholate, or methicillin and was completely inhibited by D-cycloserine or bacitracin. G Jcose was required for the inhibition by speruine of valine-C19 incorporation into cellular protein of strain S6.
doi:10.21236/ad0833372 fatcat:q3cucnohyre25c72m34xvs5wjm