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Attenuation, photon scatter, and distance-dependent collimator-detector response are major degrading factors in myocardial SPECT images. The current study investigated whether compensation for these factors improves perfusion defect detectability, and compared the results for human observers with a previous study using a mathematical observer.pmid:11884505 fatcat:kcikxtv2pbevjnqcyyqg2ih6i4