ROLE OF CBNAAT IN DIAGNOSIS OF GENITAL TUBERCULOSIS IN WOMEN

Simran Kousar, Anuradha Khanna
2021 PARIPEX INDIAN JOURNAL OF RESEARCH  
Objective: Female genital TB referring to TB of the uterus,fallopian tubes and/or Ovaries.It poses a diagnostic dilemma because of its varied presentations and lack of sensitive and specific methods of diagnosis,though CBNAAT gives rapid result. India is a country sharing one fourth of the global incidence of tuberculosis. It is much easier to diagnose pulmonary cases, but challenges are with extrapulmonary cases. Genital tuberculosis is considered as an important cause of infertility in young
more » ... fertility in young females in India and difficult to diagnose.It requires incorporation of different modalities that should correctly,timely and rapidly diagnose the case.Methods:This study was conducted prospectively from October 2016 to June 2018 on 200 endometrial samples from reproductive age group females attending Obstetrics and Gynaecology OPD in obstetrics and gynaecology department of SSH, BHU. Nucleic acid amplification technique was done and their sensitivity in diagnosis of genital tuberculosis was ascertained. Results: Out of 200 samples, 1 samples were found positive with CBNAAT.Unlike Pulmonary TB, role of CBNAAT in the diagnosis of female genital TB is limited. Conclusion: Infertility in young female per se is usually heart breaking and distressing. Therefore, it is essential to diagnose and treat the cases of genital tuberculosis before irreversible damage of tube may happen. Although, advancement in diagnostic field is there from microscopy to molecular method,but still diagnosis of genital tuberculosis is challenging. Correct diagnosis prevents young female from mental trauma and toxicity of anti-tuberculosis drugs given on suspicion in high prevalence country like India.
doi:10.36106/paripex/3401550 fatcat:f5hdjobvznda3nzmvqofm5mkuu