BNArray: an R package for constructing gene regulatory networks from microarray data by using Bayesian network

X. Chen, M. Chen, K. Ning
2006 Bioinformatics  
BNArray is a systemized tool developed in R. It facilitates the construction of gene regulatory networks from DNA microarray data by using Bayesian network. Significant sub-modules of regulatory networks with high confidence are reconstructed by using our extended sub-network mining algorithm of directed graphs. BNArray can handle microarray datasets with missing data. To evaluate the statistical features of generated Bayesian networks, re-sampling procedures are utilized to yield collections
more » ... candidate 1st-order network sets for mining dense coherent subnetworks. Availability: The R package and the supplementary documentation are available at
doi:10.1093/bioinformatics/btl491 pmid:17005537 fatcat:mrtgbyoz5zb5dcxs2b2wb5urda