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Thoracic aortic aneurysm (TAA) disease affects about 15,000 people each year.4 However, the cellular mechanism of TAA disease is not known,5 resulting in there being a high demand for research on the condition. The Akerman and Ikonomidis laboratory has demonstrated matrix metalloproteinases (MMPs) to be large players in the disease mechanism.12 As furin has been found to modulate MMP levels, this protein subsequently plays a role in TAA progression.14 However, an effective means for localizeddoi:10.17615/6qwz-sr43 fatcat:bhunnxytwrhmfnetkjrvftzjqq