Chiral Anisotropic Reagents for Determining the Absolute Configuration of Secondary Alcohols and Carboxylic Acids

Takenori Kusumi, Tetsuya Yabuuchi, Haruko Takahashi, Takashi Ooi
2005 Journal of Synthetic Organic Chemistry, Japan  
Based on the modified Mosher's method, we have developed several chiral anisotropic reagents. Together with a unique application of the modified Mosher's method to an enantiomeric mixture, utility of methoxy-(1-and 2-naphthyl)acetic acids (1NMA, 2NMA and other analogues) and phenylglycine methyl ester (PGME) in elucidation of the absolute configuration of secondary alcohols, amines, and carboxylic is summarized.
doi:10.5059/yukigoseikyokaishi.63.1102 fatcat:nad4j4m7kfdmda4ju42ssiiet4