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Aims: To evaluate the relationships between F352V polymorphism of Klotho gene, bone mineral density (BMD), and intima-media thickness (IMT) of the common carotid artery in postmenopausal women. Methods: Spine and hip BMD was assessed by dual energy X-ray absorptiometry (DXA), and IMT was measured by ultrasonography in 184 postmenopausal women. The genotyping of the Klotho gene was performed by polymerase chain reaction-restriction fragment length polymorphism. Results: Genotype frequencies weredoi:10.2478/s11536-013-0273-3 fatcat:lm4ifcli3vbnpbgixcgysnk6he