A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2019; you can also visit the original URL.
The file type is
The use of metal complexes in the pharmaceutical industry has recently increased and as a result, novel metal-based complexes have initiated an interest as potential anticancer agents. Copper (Cu), which is an essential trace element in all living organisms, is important in maintaining the function of numerous proteins and enzymes. It has recently been demonstrated that Cu complexes may be used as tumor-specific proteasome inhibitors and apoptosis inducers, by targeting the ubiquitin-proteasomedoi:10.3892/mmr.2016.6022 pmid:27959411 fatcat:pxdksqjc7zaaldlcgsnmqgibty