Applications of fluorescence lifetime imaging in clinical medicine

Zhanwen Wang, Yanping Zheng, Deqiang Zhao, Ziwei Zhao, Lixin Liu, Artem Pliss, Feiqi Zhu, Jun Liu, Junle Qu, Ping Luan
2018 Journal of Innovative Optical Health Sciences  
This article proposed a novel classification on fluorescence imaging for clinical applications, and presented a camera-based instrument to verify the functions by an animal mode. The imaging technologies of fluorescence currently are developed in biological medicine included broad-field fluorescence imaging, point-probe fluorescence imaging, and cross-sectional endoluminal fluorescence imaging respectively. This periodical's editor introduced broad-field fluorescence imaging's latest
more » ... s in technology in this issue, and illustrated a photo retouching system for decreasing the fluorescence signal-to-noise ratio in photodynamic therapy (PDT) for skin cancer. The animal test also verified that this camera-based instrument still could capture the red fluorescence under a low-dosed light sensitive drug and the scope of distribution of melanoma cells in the vein could clearly be observed.
doi:10.1142/s179354581830001x fatcat:tnptloxraneuvhpmswadsv2k2y