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Characterisation of G-Protein-coupled Receptors by Antibodies
2000
Current Medicinal Chemistry
During the past 10 years or so, associated with the introduction of molecular biology techniques to G protein-coupled receptor (GPCR) research, outstanding progress has been made in understanding the mechanisms of action of these key proteins and their physiological functions. in-vivo manipulation of levels of GPCRs using transgenic and gene knock-out approaches have been particularly successful in assessing the roles of specific GPCRs in animal physiology. Drug discovery is aiming to produce
doi:10.2174/0929867003374552
pmid:10911022
fatcat:fkoe6dnngvdgfnnijzx62qhxba