This work analyses the performance of quantum circuits and general processes to transform k uses of an arbitrary unitary operation U into another unitary operation f(U). When the desired function f a homomorphism, i.e., f(UV)=f(U)f(V), it is known that optimal average fidelity is attainable by parallel circuits and indefinite causality does not provide any advantage. Here we show that the situation changes dramatically when considering anti-homomorphisms, i.e., f(UV)=f(V)f(U). In particular, we

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... prove that when f is an anti-homomorphism, sequential circuits could exponentially outperform parallel ones and processes with indefinite causal order could outperform sequential ones. We presented explicit constructions on how to obtain such advantages for the unitary inversion task f(U)=U−1 and the unitary transposition task f(U)=UT. We also stablish a one-to-one connection between the problem of unitary estimation and parallel unitary transposition, allowing one to easily translate results from one field to the other. Finally, we apply our results to several concrete problem instances and present a method based on computer-assisted proofs to show optimality.