An axial chirality and disorder of positional isomers in a crystal of highly cytotoxic 3-acetyl-1,3-bis(2-chloro-4-nitrophenyl)-1E-triazene

Krešimir Molčanov, Slovenko Polanc, Maja Osmak, Biserka Kojić-Prodić
2015 Acta Chimica Slovenica  
Dedicated to the memory of Prof. Dr. Jurij V. Bren~i~. Abstract Biologically active 4-nitro-substituted 1,3-diaryltriazene, a chemical analogue of 1,3-bis(4'-amidinophenyl)-triazeneberenil ® , belongs to the novel, chemically modified class of potent antitumor agents. Its structural characterization by X-ray analysis and 1 H NMR spectroscopy is performed to determine molecular overall conformation in view of its possible interaction to DNA.
doi:10.17344/acsi.2015.1420 fatcat:fldbu43txbdlbntlcjgljfsiue