Large-scale production of mouse phenotypes: The search for animal models for inherited diseases in humans

M. H. de Angelis
2001 Briefings in Bioinformatics  
This paper is aimed principally at bioinformaticians and biologists as an introduction to recent advances in mouse mutagenesis, concentrating on genome-wide screens utilising the powerful mutagen N-ethyl-N-nitroso-urea (ENU). It contains a brief background to the underlying genetics as well as details of the practical aspects of organisation and data capture for such projects.
doi:10.1093/bib/2.2.170 pmid:11465734 fatcat:oadjbolkdrer5nr7vu5daoaqze