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Approach Summary Licensing status Publication and contact information Disease models Mouse model of systemic lupus erythematosus (SLE) induced by nucleic acid-containing amyloid fibrils A mouse model of SLE induced by nucleic acid-containing amyloid fibrils could help screen and evaluate potential lupus therapies. In healthy mice, immunization with DNA-containing amyloid fibrils induced a rapid interferon response, infiltration of plasmacytoid dendritic cells (pDCs) at the inoculation site,doi:10.1038/scibx.2012.882 fatcat:ogp7ue32ovbx7ouuq6npktitji