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Missense Mutation ofAbcg5in Stroke-Prone Spontaneously Hypertensive Rats Does Not Influence Lymphatic Sitosterol Absorption Regardless of the Dose: Comparison with Wistar Rats
2009
Bioscience, biotechnology and biochemistry
Preserved Fulltext
The lymphatic recovery of radiolabeled sitosterol administered in various amounts to the stomach was almost the same between stroke-prone spontaneously hypertensive rats (SHRSPs), a strain having a missense mutation in ATP binding cassette transporter g5 (Abcg5), and Wistar rats, a normal strain. The results suggest that the mutation of Abcg5 in SHRSPs, compared with Wistar rats, did not influence the ability for intestinal sitosterol absorption regardless of the dose. Key words: ATP binding
doi:10.1271/bbb.90537
pmid:19966468
fatcat:ewi7uufuvjhl3b3jhqwzdu2yzm