Brazilian Spotted Fever Prevention through a Nonlethal Capybara Population Control Strategy

Derek Andrew Rosenfield, Gina Polo, Cristiane Schilbach Pizzutto
2019 Revista da Sociedade Brasileira de Medicina Tropical  
Brazilian spotted fever (BSF), a lethal tick-borne Rickettsioses (2000 -2018 >600 human deaths) involving synanthropic capybara as host. Methods: We introduced an alternative to mitigate human-capybara conflicts and epidemiologic concerns of BSF. Complex aspects like transmission dynamics, risk areas, host mobility, and birth rate control, were considered to develop a prevention strategy using an anti-GnRH vaccine. Results: The propositioned immunocontraceptive potentially remove and prevent
more » ... spread of BSF from endemic areas. Conclusions: We propose the anti-GnRH vaccine as a BSF prevention strategy based on these favorable results.
doi:10.1590/0037-8682-0156-2019 fatcat:2slxfplpmndafo3tpk7qeegu7i