Abstract: Cardiorenal continuum is the most discussed area in the field of internal medicine when it comes to comorbidity in the last 10 years. Cardiovascular diseases, obesity, type II diabetes, and kidney dysfunction are becoming more and more pandemics of the 21st century. In recent years, the main cause of renal dysfunction is not its primary disease, but hypertension, which means essential arterial hypertension and diabetes Mellitus.