Borreliosis is characterized by a variety of clinical symptoms affecting the skin (erythema chronicum migrans, lymphadenopathia cutis benigna, acrodermatitis chronica atrophicans), eyes (conjunctivitis, iritis, uveitis), muscles (myositis), nervous system (neuritis, radiculitis, polyradiculitis, meningopolyralitis ), joints (arthritis, arthralgia) and heart (carditis). The variety of symptoms is explained by the difference in the subspecies Borrelia burgdorferi sensu lato in virulence and

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... tropism and changes in the patient's immune response. The main subspecies Borrelia burgdorferi sensu lato (B.b.s.l.) are Borrelia burgdorferi sensu stricto (B.b.s.s.), Borrelia burgdorferi garinii (B.b.g.) and Borrelia burgdorferi afzelii (B.b.a.). In North America, only B.b.s.s. has been found, while all 3 species can be found in Europe. Epidemiological studies have shown that the number of patients with borreliosis is still increasing, which is associated with an increase in the density of distribution of tick vectors, which are carriers of the disease, and with the degree of awareness of people.