P. G. Department of Studies in Chemistry, Karnatak University, Dharwad-580 003, Karnataka, India E-mail: kbgudasi@rediffmail.com Fax : 91-836-721275 Manuscript received 18 July 2005, revised 10 January 2006, accepted 16 January 2006 The metal complexes of UOII2 and ThIv with Schiff bases derived from 2-aminopyridine and acetophenone/a-hydroxy acetophenone/a-amino acetophenone have been synthesized and characterized on the basis of elemental analyses, conductivity, IR,electronic aud 1H NMR

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... al studies. The evidences show that the complexes with acetophenone and o-hydroxy acetophenone Schiff bases exhibit coordination number eight while coordination number ten with o-ami no acetophenone Schiff bases. A comparative study of testicular atrophy in albino rats by the chelating agents and the corresponding UOII2 and ThIv complexes was carried out. A considerable reduction in the testes weight and weight of some accessory sex organs was observed. The effect is more with the complexes than with the ligands.