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Conserved units of co-expression in bacterial genomes: an evolutionary insight into gene regulation
[article]
2014
bioRxiv
pre-print
Genome-wide measurements of transcriptional activity in bacteria indicate that the transcription of successive genes is strongly correlated beyond the scale of operons. However, the underlying mechanisms are poorly characterized and a systematic method for identifying local groups of co-transcribed genes is lacking. Here, we identify supra-operonic segments of consecutive genes by comparing gene proximity in thousands of bacterial genomes. Structurally, the segments are contained within
doi:10.1101/012526
fatcat:o5e7e6nv65cupmddtvj2lvsbjq