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High Potency Neuroleptics and Violence in Schizophrenics
1988
Journal of Nervous and Mental Disease
In a conti'olled stucly, inpatient violence was measured cluring placebo, high-potency (halopericlol) and lorv-potency (chlorpromazine or clozapine) neuroleptics. Some patients had a markecl increase in violent behavior rvith the mocleratelv high-dose haloperidol, but not u,ith lou,-potency neuroleptics. The authors cliscuss reasons for the inct'easecl vioience rvith halopericlol, inclucling al<athisia ancl clmg-induced behavioral toxicit.y.
doi:10.1097/00005053-198809000-00009
fatcat:wqfgc4o6x5bvjknb5nqmi3ip5a