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Comparison of COPD and Lung Cancer Mechanisms for Identifying MicroRNA Biomarkers By The Reconstruction of miRNA-mRNA Co-Expression Network
Background: The association between lung cancer and chronic obstructive pulmonary disease (COPD) is now well established; as people with COPD are more likely to develop lung carcinoma. However, the evidence for this relationship is inconclusive and there is currently little information on the underlying molecular mechanisms. MicroRNAs (miRNAs) are one of the regulatory factors in lung cancer and COPD that their functions are widely studied in many chronic diseases and cancers. Rationally,doi:10.21203/rs.3.rs-239948/v1 fatcat:klewudyvpja43a5oz6dkvunqtm