: This study was done with the aim of investigating the role of cognitive and emotional deficiencies in anticipation of membership in addicted and non-addicted groups. Materials and Methods: This fundamental and reviewing type research is a cross-sectional comparative study that was performed retrospectively. Population of the study was all the male substance abusers referred to addiction treatment centers in one of the cities of Lorestan province in 2014. The selected population included 100

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... substance abusers and 100 normal people (from the patients, accompanies) selected by purposive sampling method. All participants completed cognitive failures questionnaire (CFQ) and alexithymia questionnaire (TSA-20). The point analysis was applied to analyze the data. Analysis was performed using SPSS-20. Results: In point analysis at simultaneous method, seven predicting variables (difficulty in describing and identifying feelings, thoughts turned to the outside, memory problems, distractibility, oversight and not reminding the names) and in the stepwise method, three predicting variables (cognitive failures, difficulty in describing feelings and memory problems) for the only function of the point is explained by the difference between two groups of addicted and non-addicted. Conclusion: The results showed that addicts and non-addicts can be distinguished from cognitive and emotional impairment.