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Machine learning guided batched design of a bacterial Ribosome Binding Site
[article]
2022
bioRxiv
pre-print
Optimisation of gene expression levels is an essential part of the organism design process. Fine control of this process can be achieved through engineering transcription and translation control elements, including the ribosome binding site (RBS). Unfortunately, design of specific genetic parts can still be challenging due to lack of reliable design methods. To address this problem, we have created a machine learning guided Design-Build-Test-Learn (DBTL) cycle for the experimental design of
doi:10.1101/2022.01.05.475140
fatcat:ntg4tf26pndvtg6gb74urpefom