Elephantid Genomes Reveal the Molecular Bases of Woolly Mammoth Adaptations to the Arctic

Vincent J. Lynch, Oscar C. Bedoya-Reina, Aakrosh Ratan, Michael Sulak, Daniela I. Drautz-Moses, George H. Perry, Webb Miller, Stephan C. Schuster
2015 Cell Reports  
Graphical Abstract Highlights d Complete genomes of three Asian elephants and two woolly mammoths were sequenced d Mammoth-specific amino acid changes were found in 1,642 protein-coding genes d Genes with mammoth-specific changes are associated with adaptation to extreme cold d An amino acid change in TRPV3 may have altered temperature sensation in mammoths
doi:10.1016/j.celrep.2015.06.027 pmid:26146078 fatcat:f5nefsxf7zcs3hfamquiwee6oy