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Polioencephalomalacia (PEM) is a nervous disease with neuronal necrosis. He previously believed that this condition was related to thiamine deficiency, but studies suggest that it can be determined by different nutritional and dietary factors. In this context, objectified to perform a literature review on the main causes of polioencephalomalacia caused by nutritional and dietary factors as well as the appropriate treatment and prevention in ruminants. Therefore, PEM disease can be caused by thedoi:10.36560/13420201042 fatcat:jr4orpgtu5ggnavp75qcfru57q