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Esomeprazole is a BCS 11 compound, proton pump inhibitor used in the treatment of gastric, duodenal ulcer. The half-life of the drug is 4 hour. The drug has poor stability in acidic condition of the stomach. So, it is formulated into small sized and efficient carriers: the microspheres. To improve their residence time, bioadhesive characteristics can be coupled to develop mucoadhesive microspheres. Mucoadhesive microspheres are extensively used in targeted drug delivery due to their advantagesdoi:10.5281/zenodo.3477822 fatcat:yebv7xa2wndgpjairziznc56fi