Prevalence of HBs Antigen, and HCV and HIV Antibodies in a Young Male Population in Cameroon

Dominique Noah Noah, Firmin Ankouane Andoulo, Brice Valery Moussima Essoh, Georges Nko'O Ayissi, Servais Albert Fiacre Eloumou Bagnaka, Magloire Biwole Sida
2015 Open Journal of Gastroenterology  
According to WHO estimates, 57% of cases of liver cirrhosis and 78% of primary liver carcinoma are caused by a hepatitis B or C virus. This study aimed to assess the prevalence of these diseases and HIV among a young male population, according to region. Methods: This was a descriptive cross-sectional study conducted from 17 February to 31 March 2014 in the ten administrative regions of Cameroon. The study included male subjects of Cameroonian nationality aged at least 18 and at most 23, and
more » ... at most 23, and living in the regions concerned. It excluded subjects that did not match the age, gender, and nationality criteria. For each subject, 10 ml of blood was collected in a dry tube. After centrifugation at 3000 RPM for 5 minutes, the serum was collected for the detection of viral infections. For subjects that tested positive, a confirmatory test was conducted. Results: In total, 4367 subjects were selected, with an average age of 20.46 (+/− 1.17) years. The prevalence of hepatitis B virus stood at 13.01% (with 95% CI: 12.03% -14.05%). That of viral hepatitis C was 0.30% (95% CI: 0.17% -0.52%). Co-infection with hepatitis B and C viruses was 0.05% (95% CI: 0.01% -0.18%). The prevalence of HIV infection was 1.01% (95% CI: 0.74% -1.36%). Conclusion: The overall prevalence of HBsAg in the population of young males is high. It tallies with the early vertical and horizontal modes of transmission that prevail in our environment.
doi:10.4236/ojgas.2015.512028 fatcat:s234okch3ngvljbb6beixpnduq