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The aim of the present study was to investigate the effect of ellagic acid on haloperidol-induced orofacial dyskinesia and catalepsy in Wistar male albino rats and to explore the possible underlying mechanisms for these effects. Haloperidol (1 mg/kg, ip) was administered on 21 successive days to induce orofacial dyskinesia in rats. Ellagic acid (10, 20 and 40 mg/kg, po) was administered for 21 successive days to separate groups of haloperidol treated rats. Haloperidol significantly induceddoi:10.7897/2277-4343.07292 fatcat:kuuq4mnn6fcppltx3fvpselpam