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A high-performance liquid chromatographic method was applied to the determination of stachydrine hydrochloride concentration in TJF granule (Chinese name: Tiao-Jing-Fang), using a mobile phase of methanol-acetonitrile (50:50, v/v) by the Agilent Kro-masi NH 2 column (250 mm × 4.6 mm, 5 μm, S/N: 22N25110). Detection wavelength was 201 nm. The result revealed good linearity of stachydrine hydrochloride and was obtained within the range of 0.20 -1.98 μg/mL (R = 0.9995). The average recovery wasdoi:10.4236/pp.2013.43040 fatcat:3qhuqcckw5ajfkhqe5ci7xsb34