One feature of cloud storage systems is data fragmentation (or sharding) so that data can be distributed over multiple servers and subqueries can be run in parallel on the fragments. On the other hand, flexible query answering can enable a database system to find related information for a user whose original query cannot be answered exactly. Query generalization is a way to implement flexible query answering on the syntax level. In this paper we study a clustering-based fragmentation for the

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... eralization operator Anti-Instantiation with which related information can be found in distributed data. We use a standard clustering algorithm to derive a semantic fragmentation of data in the database. The database system uses the derived fragments to support an intelligent flexible query answering mechanism that avoids overgeneralization but supports data replication in a distributed database system. We show that the data replication problem can be expressed as a special Bin Packing Problem and can hence be solved by an off-the shelf solver for integer linear programs. We present a prototype system that makes use of a medical taxonomy to determine similarities between medical expressions.