Response to Letters Regarding Article, "Anticoagulation and Survival in Pulmonary Arterial Hypertension: Results From the Comparative, Prospective Registry of Newly Initiated Therapies for Pulmonary Hypertension (COMPERA)"

K. M. Olsson, M. Delcroix, H. A. Ghofrani, H. Tiede, D. Huscher, R. Speich, E. Grunig, G. Staehler, S. Rosenkranz, M. Halank, M. Held, T. J. Lange (+16 others)
2014 Circulation  
postulate that the 21% reduction in mortality observed in patients with idiopathic (IPAH) pulmonary arterial hypertension (PAH) who received anticoagulants was mainly the result of immortal time bias rather than a true drug effect. We can assure them that this was not the case. Anticoagulation was started within 3 months after diagnosis in 92.4% of all patients (94.8% after 6 months and 97.4% after 12 months).
doi:10.1161/circulationaha.114.010921 pmid:25223780 fatcat:rkasapnpznbvhbiicddl36njze