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Severe combined immune deficiency (SCID), also known as alymphocytosis, Glanzmann-Rinker syndrome, and thymic alymphoplasia, is characterized by impairment in the differentiation of T, B lymphocytes, and natural killer cells. Adenosine deaminase deficiency is the most common cause of SCID, as it leads to dysfunction of T, B lymphocytes and severe lymphopenia. Due to the severity of the disease, early diagnosis is essential to provide desired treatment and get a good therapeutic outcome. Theydoi:10.32677/ijcr.2020.v06.i06.014 fatcat:4tuzxwyo6na2dagnyxlnujricq