Pure Red Cell Aplasia After ABO Major-Mismatched Allogeneic Peripheral Blood Stem Cell Transplantation Successfully Treated with Plasma Exchange and Low-Dose Steroid: Two Case Reports

Hui-Jen Tsai, Sheng-Fung Lin, Ta-Chih Liu, Chao-Sung Chang, Hui-Hua Hsiao, Tyen-Po Chen
2004 Kaohsiung Journal of Medical Sciences  
Pure red cell aplasia (PRCA) is a complication of ABO-incompatible allogeneic stem cell transplantation. The mechanism is not well known, although the isoagglutinin titer before transplantation or cyclosporine use is considered to be the cause. Patients with this complication require more blood transfusions than those without it. There is no standard treatment. We report two cases of PRCA after allogeneic peripheral blood stem cell transplantation that were successfully treated with plasma exchange and low-dose steroid.
doi:10.1016/s1607-551x(09)70096-8 pmid:15124897 fatcat:7ar26rg65vb27fjjnmqjxnibue