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EmpiReS: Differential Analysis of Gene Expression and Alternative Splicing
[article]
2020
bioRxiv
pre-print
While absolute quantification is challenging in high-throughput measurements, changes of features between conditions can often be determined with high precision. Therefore, analysis of fold changes is the standard method, but often, a doubly differential analysis of "changes of changes" is required. Differential alternative splicing is an example of a doubly differential analysis, i.e. fold changes between conditions for different isoforms of a gene. EmpiRe is a quantitative approach for
doi:10.1101/2020.08.23.234237
fatcat:ibi2eug5bzc5pft4ijchbqim6i