Simultaneous magnetic particles washing and concentration in a microfluidic channel

Qasem Ramadan, M.A.M. Gijs
2009 Procedia Chemistry  
Purification of magnetic microparticles was demonstrated, with a purification efficiency of (72±14) % at a flow rate of 3 µl/min, in a microfluidic chip using a rotational magnetic system under continuous flow conditions. The rotation of a periodically arranged magnetic assembly close to a fluidic channel carrying magnetic particles suspension allows the trapping and releasing of particles in periodical manner, leaving other particles to be discarded in the waste. Each trapping and releasing
more » ... nt resembles one washing cycle in a conventional biological assay.
doi:10.1016/j.proche.2009.07.374 fatcat:eyic7hsfdfb7vmhufnqoirkq4m