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Muscle damage impairs insulin stimulation of IRS-1, PI 3-kinase, and Akt-kinase in human skeletal muscle
American Journal of Physiology. Endocrinology and Metabolism
Muscle damage impairs insulin stimulation of IRS-1, PI 3-kinase, and Aktkinase in human skeletal muscle. Am J Physiol Endocrinol Metab 279: E206-E212, 2000.-Physiological stress associated with muscle damage results in systemic insulin resistance. However, the mechanisms responsible for the insulin resistance are not known; therefore, the present study was conducted to elucidate the molecular mechanisms associated with insulin resistance after muscle damage. Muscle biopsies were obtained beforedoi:10.1152/ajpendo.2000.279.1.e206 pmid:10893341 fatcat:4woxsmx44veffn4etfflav6ywe