Myopericytoma arising from myopericytosis—a hitherto unrecognized entity within the lung

Ulrike Gruber-Moesenbacher, Alicia Morresi- Hauff, Katja Behr, Helmut Popper
2020 Virchows Archiv  
AbstractTwo cases of myopericytosis combined with pericytoma originating within the lung are reported. These are rare pulmonary tumors. The differential diagnosis for hemangiopericytoma and pericytic tumors with glomus elements is discussed. Both myopericytic lesions mimic other lesions, which are more commonly seen in the lung. Based on the expression of vascular growth factor receptors 2 and 3, an antiangiogenic therapy was suggested for the patient with the myopericytoma. A treatment with an
more » ... angiogenesis inhibitor resulted in a regression of the tumor, but not the precursor lesion. Probably a more specific therapy using tyrosine kinase inhibitors for VEGFR2/3 might better control these myopericytic proliferations.
doi:10.1007/s00428-020-02972-9 pmid:33244708 fatcat:ghim6ttaqjesjfzcisuiraefbq