An automated algorithm for the computation of brain volume change from sequential MRIs using an iterative principal component analysis and its evaluation for the assessment of whole-brain atrophy rates in patients with probable Alzheimer's disease

Kewei Chen, Eric M Reiman, Gene E Alexander, Daniel Bandy, Rosemary Renaut, William R Crum, Nick C Fox, Martin N Rossor
2004 NeuroImage  
the disease-modifying effects of putative treatments, and investigating the course of other normal and pathological changes in brain morphology. D 2004 Elsevier Inc. All rights reserved.
doi:10.1016/j.neuroimage.2004.01.002 pmid:15110003 fatcat:evoe7bwl45bxln467gp5f5mpda