Prevalence and Risk Factors in a Single Center Study of Female Patients with Osteoporotic Fracture

Dr. Md. Asaduzzaman, Dr. Tasnuva Akter, Dr. Mohammad Sayem, Dr. Biswajit Barai
2022 SAS Journal of Surgery  
The prevalence of osteoporotic fracture, its sociodemographic associations, and its associated complications among Bangladeshi women are little known. The National Institutes of Health (NIH) defines osteoporosis as a skeletal disease characterized by decreased bone mass and a deterioration of the micro-architectural bones that causes reduced bone strength and an increased risk of fragility fractures of the hip, spine, and wrist. Objective: We determined the prevalence and risk factors according
more » ... to fracture site and evaluated the associated risk factors in female patients with osteoporotic fractures. Methods: A cross‑sectional and community‑based study was conducted among the Bangladeshi females aged from 20‑65 years in Dhaka and Munshiganj. Between July 2020 and June 2021, we evaluated 50 patients who were diagnosed with hip (femoral neck or intertrochanteric), spine (vertebrae) or wrist (distal radius fractures) and who underwent surgery or conservative treatment. The assessment was conducted using questionnaire. Statistical analyses were conducted with SPSS for Windows statistical package, version 24.0 (SPSS Inc., Chicago, IL, USA). This study was approved by the Institutional Review Board of each hospital, which waived informed consent. Results: In this study 41.5% (17/41) had hip fractures, 35% (14/40) had spine fractures, and 29.6% (8/27) had distal radius fractures. Body mass index (BMI; P=0.036) and prevalence of chronic kidney disease (CKD; P=0.046) and rheumatoid arthritis (P=0.051) were significantly different between the groups. In multivariable analysis, BMI (odds ratio [OR], 0.76; 95% confidence interval [CI], 0.55-1.05, P=0.098) and CKD (OR 2.51; 95% CI, 0.38-16.2; P=0.233) were associated with an increased risk of factors; however, this was not statistically significant. Conclusion: In patients with osteoporotic fractures, this study evaluated the prevalence according to the fracture area and found associated risk factors.
doi:10.36347/sasjs.2022.v08i09.003 fatcat:m7orxtrf5zgnxgo4heznpwv4pq