New curtachalasin from the Xylaria sp. DO 1801

Jia Wang, Yining Sang, Siqi Tang, Peng Zhang
2020 Figshare  
One new cytochalasin, named curtachalasin Q (1), together with 8 known cytochalasins were isolated from the ethyl acetate extract of the Xylaria sp. DO1801. The structure of the new compound was elucidated on the basis of IR, UV, HR-ESI-MS, NMR spectra and X-ray diffraction. Compound 1 and 2 were not cytotoxic (IC50>50uM) against four tumour cell lines (SW-1990, ASPC-1, HepG2 and Hep3B).
doi:10.6084/m9.figshare.11912259 fatcat:cpmqscy7pbao7mbu25sk4sq7pu