An overview of the pathogenesis of thyroid autoimmunity

Giulia Cogni, Luca Chiovato
the organ-specific enzyme thyroid peroxidase (TPO), and the TSH-receptor (TSH-R). 3 In the first years of this century, the sodium-iodide symporter was also shown to behave as a thyroid-specific auto-antigen. 4 More recently, autoantibodies to pendrin, an iodide transporter located at the apical pole of thyroid follicular cells, were identified in the majority of patients with HT and GD. 5
doi:10.1007/bf03401283 fatcat:onpgaxdnjzfx7kiqjs6mocds5i