Creating an environment of innovation in the outlook of our people is our most important task. Without innovation, there will be no competition, no development -Shavkat Mirziyoev, President of the Republic of Uzbekistan Abstract: At present, numerous approaches have been verified and suggested in relation to the innovation policy formulation of enterprise. However, less attention is paid to regions in developing world. An attempt is made in this thesis towards that direction. I argue that from

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... ystem of innovation theory perspective, innovation policy practice for regions in developed world is a problem solving based process, due to the path dependency of innovation policy and the development level of advanced economies. By this purpose, the article proves the possibility of every company's making much more profit by realizing and improving effective innovative management in the developing economy. And, it will be calculated and assessed the correlation link between the costs of innovation and total revenues of the world's most innovative companies. At the end it will be done some conclusions and discussions of nowadays innovators practice.