Citation: Nikkhah A. Wrecked Oncogenesis through Synchronized Substrate Availability and Oxidation: A Novel

Austin Journal, Biotechnology Bioengineering
2015 Bioengineering of Cell Physiology. Austin J Biotechnol Bioeng   unpublished
Oncogenesis is driven by genetic and epigenetic alterations and occurs via gene expression dysregulation. Genotoxic agents, chromosome related abnormalities, pattern of methylation, diet and other environmental and nutritional factors contribute to carcinogenesis. This article innovatively describes how asynchrony between cell substrate availability and oxidation triggers known and unknown oncogenic mechanisms that may ultimately cause cancer.