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Fibromyalgia patients with high levels of anti-satellite glia cell IgG antibodies present with more severe symptoms
[article]
2022
bioRxiv
pre-print
Objective: Transferring fibromyalgia patient IgG to mice induces pain-like behaviour and fibromyalgia IgG binds mouse and human satellite glia cells (SGCs). These findings suggest that autoantibodies could be part of fibromyalgia pathology. However, it is unknown how frequently fibromyalgia patients have anti-SGC antibodies and how anti-SGC antibodies associate with disease severity. Methods: We quantified serum or plasma anti-SGC IgG levels in two fibromyalgia cohorts from Sweden and Canada
doi:10.1101/2022.07.06.498940
fatcat:3canvfyss5dxxnxc5qssnvlrga