THE NEUROPROTECTIVE EFFECT OF HYDRO-ALCOHOLIC EXTRACTS OF CANTHARELLUS CIBARIUS ON NEURONAL DENSITY OF ALPHA MOTONEURONS IN SPINAL CORD ANTERIOR HORN AFTER SCIATIC NERVE COMPRESSION IN RATS

Alireza Ajami, Maryam Tehranipour
unpublished
This aim of this study is carried out to examine the neuroprotective effects of hydro-alcoholic extract of Cantharellus cibarius on neuronal density of motoneuron in spinal cord anterior horn in rats. This experimental research, was carried out on 30 male Wistar rats. Rats were divided into five groups each consisting six member. A: control, B: Compression, C: Compression + treatment with 50,75,100 mg\kg Hydro alcoholic extract. After 4 weeks post-operative the lumbar segments of spinal cord
more » ... s of spinal cord were sampled, processed, sectioned serially and stained with toluidine blue (pH 4.65). By using stereological quantitative technique, the number of alpha motoneurons in the right horn of spinal cord were counted and compared with each other. Statistical analysis showed remarkable increase in the number of alpha motoneurons in the groups with dosage (100 mg\kg) in compared to compression. Result shows that hydro-alcoholic extract could increase neuronal density motoneuron in anterior horn of spinal cord after sciatic nerve injury in rat.
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