In a dynamic analysis of biological sample using finite element method, generally biological mesh models are made of X ray CT or MNI image data. These images resolution are about 1 mm, but some biological tissues' sizes are less than 1 mm. In this study, we proposed digitizing with 3dimention internal structure microscope (3D-ISM). This device slices a fixed sample, and obtains a cross -sectional image that is μm order. In addition, we propose the method of generating the mesh model of high

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... racy from the observation data of 3D-ISM as it is semiautomatic. Shape and quality were compared by voxel mesh and mapped mesh. As for shape mapped mesh can represent detail of each eye tissue. As for quality voxel mesh is constancy. In mapped mesh, we compared three type of shape before project, in order to examine whether it is applicable to general tissue. A coarse model is least distortion of an inner side and an outside, and considered that each individual difference of tissue is absorbable.